Newly identified protein could become target for cancer immunotherapy
Posted by Charles Decuir on June 7, 2021 3:40 PM EDT
Researchers have found a protein that, when inhibited in mice with cancer, increased the response to immunotherapy.
Researchers at the Francis Crick Institute, UK, have identified a protein that helps tumours evade the immune system and in certain types of cancers, is linked to a poorer chance of survival. The team say that the protein could become a target for future cancer treatments.
According to the researchers, a crucial part of the immune system’s response to cancer is a group of white blood cells, called CD8+ T cells, which kill tumour cells. Before they launch their antitumour response, these cells must be what to attack by another immune cell, a dendritic cell.